[Neurological symptoms with a hepatitis E virus infection]

Area of Science:

• Zoonotic diseases
• Neurology
• Infectious diseases

Background:

• Hepatitis E virus genotype 3 (HEV3) is an emerging zoonotic infection in industrialized nations.
• HEV3 infections are typically asymptomatic.
• Neurological symptoms are known extrahepatic sequelae of HEV3.

Observation:

• A 52-year-old male presented with bilateral shoulder and arm pain, weakness, and sensory disturbances.
• The patient was diagnosed with bilateral neuralgic amyotrophy.
• The neurological condition was associated with an HEV3 infection.

Findings:

• HEV3 infection can manifest with neurological complications.
• Bilateral neuralgic amyotrophy is a potential neurological sequela of HEV3.
• The incidence and full spectrum of HEV3 neurological symptoms require further investigation.

Implications:

• This case expands the known spectrum of neurological manifestations of HEV3 infection.
• Increased awareness of HEV3-associated neurological sequelae is crucial for timely diagnosis and management.
• Further research is needed to understand the pathogenesis and epidemiology of HEV3 neurological complications.