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Updated: Mar 18, 2026

Fabrication of Engineered Vascular Flaps Using 3D Printing Technologies
Published on: May 19, 2022
Hierarchical Fabrication of Engineered Vascularized Bone Biphasic Constructs via Dual 3D Bioprinting: Integrating
Haitao Cui1, Wei Zhu1, Margaret Nowicki1
1Department of Mechanical and Aerospace Engineering, The George Washington University, 3590 Science and Engineering Hall 800 22nd Street NW, Washington, DC, 20052, USA.
Abstract:
A biphasic artificial vascularized bone construct with regional bioactive factors is presented using dual 3D bioprinting platform technique, thereby forming a large functional bone grafts with organized vascular networks. Biocompatible mussel-inspired chemistry and "thiol-ene" click reaction are used to regionally immobilize bioactive factors during construct fabrication for modulating or improving cellular events.

