Normal thyroid function in 32 patients with amyotrophic lateral sclerosis

Thyroid function tests were evaluated in 32 patients with amyotrophic lateral sclerosis (ALS) with radioimmunoassay of triiodothyronine, thyroxine, thyroid-stimulating hormone, and free thyroxine. The presence of antithyroid antibody activities were also tested. All patients were found to have normal thyroid values except one, who had low triiodothyronine and all patients had negative for antithyroid antibody activities. The data suggest that ALS could not be related to a thyroid disorder.