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Leiomyosarcoma in the mandible: A rare case report
Bogumił Lewandowski1, Robert Brodowski, Paweł Pakla
1Department of Maxillo-Facial Surgery, Fr. Chopin Clinical Voivodeship Hospital Chair of Emergency Medical Service, Faculty of Medicine, the University of Rzeszow Department of Radiotherapy, Subcarpathian Oncology Centre, Rzeszow, Poland.
Medicine
|July 12, 2016
Summary
This case report details a rare maxillofacial leiomyosarcoma (LMS) in a 58-year-old female. Successful combined surgical and radiotherapy treatment resulted in no recurrence over a 3-year follow-up period.
Area of Science:
- Oncology
- Oral and Maxillofacial Surgery
- Pathology
Background:
- Leiomyosarcoma (LMS) is a rare malignancy, particularly in the maxillofacial region.
- Maxillofacial LMS often presents with non-specific symptoms, complicating early diagnosis.
Observation:
- A 58-year-old female presented with a painless left mandibular tumor causing facial asymmetry.
- Deterioration of lower denture fit was a notable symptom over several months.
Findings:
- Diagnostic imaging (CT, MRI, ultrasound, pantomography) and histopathology confirmed primary leiomyosarcoma of the mandible.
- The patient underwent successful surgical resection followed by adjuvant radiotherapy (60 Gy in 35 fractions).
Implications:
- This case highlights the importance of considering rare malignancies in maxillofacial diagnostics.
- The successful treatment and 3-year disease-free follow-up contribute valuable experience for managing craniofacial LMS.

