Related Experiment Video
Updated: Mar 18, 2026
04:04
Asthma Detection Research Based on Voice Signal Processing and Machine Learning
Published on: July 22, 2025
1.2K
The path to personalized medicine in asthma
Diego Bagnasco1, Matteo Ferrando1, Stefano Bernardi1
1a Allergy & Respiratory Diseases, DIMI, Department of Internal Medicine , University of Genoa, IRCCS AOU San Martino - IST , Genoa , Italy.
Expert Review of Respiratory Medicine
|July 12, 2016
Summary
Asthma treatment is advancing towards precision medicine. New biological drugs target specific inflammatory pathways, moving away from a one-size-fits-all approach for better patient outcomes.
Area of Science:
- Pulmonology and Immunology
- Respiratory Medicine
Background:
- Asthma affects approximately 10% of the population, with severe forms in up to 10% of cases.
- Recent research deepens the understanding of asthma's pathophysiological mechanisms.
- Two patient groups are identified based on inflammatory drivers, enabling targeted cellular interventions.
Purpose of the Study:
- To review current advancements in asthma treatment.
- To highlight the shift towards precision medicine in asthma care.
- To discuss emerging biological therapies and combination strategies.
Main Methods:
- Review of current literature on asthma pathophysiology and treatment.
- Analysis of emerging biological drugs targeting specific inflammatory pathways (IgE, IL-4, IL-5, IL-13, IL-17).
- Discussion of the transition from generalized to personalized asthma management.
Main Results:
- Understanding of asthma pathophysiology has led to the development of targeted biological drugs.
- Several biological agents targeting key cytokines are under investigation.
- The paradigm is shifting towards precision medicine for asthma.
Conclusions:
- Asthma therapy is evolving into a precision medicine model.
- Future treatments may involve sequential or combination bio-therapies for individual patients.
- Targeted interventions promise more effective management of diverse asthma phenotypes.
Related Concept Videos
01:29Asthma-I: Introduction
3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
01:30Asthma-IV: Diagnostic and Management
3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
01:20Asthma: Pathogenesis and Management
1.6K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.6K
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
2.3K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.3K
01:26Asthma-II: Pathophysiology and Classification
4.8K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.8K
01:30Asthma-IV: Nursing Management
4.0K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
4.0K