Related Experiment Videos
Total Synthesis of the Illicium-Derived Sesquineolignan Simonsol C
Jeremy Nugent1, Martin G Banwell1, Brett D Schwartz1
1Research School of Chemistry, Institute of Advanced Studies, The Australian National University , Canberra, ACT 2601, Australia.
Organic Letters
|July 12, 2016
Abstract:
The racemic form of the title natural product 1 has been synthesized by engaging, as a key step, the iodoarene-tethered cyclohexene 22 in an intramolecular Heck reaction to give compound 23. This angularly substituted tetrahydrodibenzo[b,d]furan was elaborated over a further five steps into target (±)-1.