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Updated: Mar 18, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
From Femoral to Radial Approach in Coronary Intervention
Renatomaria Bianchi1, Ludovica D'Acierno1, Mario Crisci1
11 Division of Cardiology, Second University of Naples, A.O. dei Colli Monaldi Hospital, Naples, Italy.
Insights
Transradial access offers superior outcomes for cardiac catheterization compared to transfemoral access. This minimally invasive technique reduces complications, shortens hospital stays, and enhances patient comfort, making it a preferred method for coronary angiography.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Procedures
Background:
- Cardiac catheterization has evolved significantly since its inception in 1929.
- Historically, transfemoral access was standard, but transradial access is gaining prominence due to its benefits.
Purpose of the Study:
- To review and compare the efficacy, safety, and cost-effectiveness of transradial versus transfemoral access for cardiac catheterization.
- To analyze patient data and incorporate findings from the Minimizing Adverse hemorrhagic events by TRansradial access site and systemic implementation of angioX (MATRIX) study.
Main Methods:
- Systematic literature review on transradial and transfemoral access.
- Analysis of patient data, including outcomes from the MATRIX study.
- Comparative assessment of complication rates, hospitalization duration, and patient comfort.
Main Results:
- Transradial access demonstrated superiority over transfemoral access.
- Key advantages include reduced access site complications, shorter hospital stays, and improved patient comfort.
- Increased operator experience further mitigates procedural risks associated with the transradial approach.
Conclusions:
- Transradial access is an excellent and safer option for coronary angiography.
- The benefits of transradial access, particularly in reducing complications and improving patient experience, are well-established.
- Continued adoption and operator experience are crucial for maximizing the advantages of this technique.
Abstract:
Since the first cardiac catheterization in 1929, this procedure has evolved considerably. Historically performed via the transfemoral access, in the last years, the transradial access has been spreading gradually due to its many advantages. We have conducted a review of published literature concerning efficacy, safety, and cost-effectiveness, and we analyzed our patients' data, including the results of the recently published Minimizing Adverse hemorrhagic events by TRansradial access site and systemic implementation of angioX (MATRIX) study. This review confirmed the superiority of the transradial access compared to the femoral access, especially regarding complications related to the access site, duration of hospitalization, and comfort for the patient. The transradial approach is an excellent option for coronary angiography, and the procedure's risks are reduced by increased operator experience.
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