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Updated: Mar 18, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Malignant adnexal carcinomas of the skin]
Anders Klit1, Ann Hærskjold, Ulrikke Lei
1anders.klit@regionh.dk.
Abstract:
Malignant adnexal carcinomas of the skin are rare but associated with high propensity for local recurrence, and for some of the distinct subgroups they are known to metastasize regionally or distant. Biopsy is necessary for correct diagnosis, as the lesions cannot be separated from other tumour types entirely on their clinical appearance. The histologic diagnosis is troublesome, and the lesions are often mistaken for their benign counterpart, basal cell carcinoma or squamous cell carcinoma. The lesions are treated with surgery. Radiotherapy and chemotherapy may play a role in treatment, although the evidence is limited.
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