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Nasal Bacterial Colonization in Pediatric Epistaxis: The Role of Topical Antibacterial Treatment
Mukadder Korkmaz1, Yeliz Çetinkol2, Hakan Korkmaz1
1Department of Otorhinolaryngology, Ordu University School of Medicine, Ordu, Turkey.
Insights
Recurrent epistaxis in children is common, but nasal Staphylococcus aureus colonization did not influence bleeding resolution or treatment outcomes. Topical antibacterial treatments showed no advantage over non-antibacterial options for pediatric epistaxis.
Area of Science:
- Otolaryngology
- Pediatric Medicine
- Microbiology
Background:
- Epistaxis (nosebleeds) is a frequent childhood ailment.
- Recurrent epistaxis in children is associated with nasal Staphylococcus aureus colonization.
- Bacterial colonization may contribute to epistaxis through inflammation, crusting, and vascularity.
Purpose of the Study:
- To examine nasal bacterial colonization in pediatric epistaxis patients.
- To evaluate treatment outcomes in relation to nasal colonization.
Main Methods:
- Retrospective cross-sectional study of pediatric epistaxis patients.
- Review of patient charts from otolaryngology outpatient clinics.
- Analysis of nasal cultures taken at the initial visit.
Main Results:
- Staphylococcus aureus was the predominant bacteria identified.
- Nasal crusting and hypervascularity were not linked to bacterial growth.
- Bleeding resolution was independent of nasal colonization status.
- Topical antibacterial and non-antibacterial treatments yielded similar outcomes.
Conclusions:
- High rates of nasal colonization do not correlate with improved outcomes using topical antibacterials.
- The study does not support a link between bacterial colonization, nasal hypervascularity, and epistaxis in children.
- Further research is needed to clarify the role of bacterial colonization in pediatric epistaxis and guide treatment protocols.
Background:
Epistaxis is a common problem in childhood. It has been shown that children with recurrent epistaxis are more likely to have nasal colonization with Staphylococcus aureus. It has been suggested that low-grade inflammation, crusting and increased vascularity due to bacterial colonization contributes to the development of epistaxis in children.
Aims:
This study aimed to investigate the nasal colonization and treatment outcome in pediatric epistaxis patients.
Study Design:
Retrospective cross-sectional study.
Methods:
Charts of the pediatric patients referred to our university hospital otolaryngology outpatient clinics for the evaluation of epistaxis were reviewed. The patients whose nasal cultures had been taken at the first clinical visit comprised the study group.
Results:
Staphylococcus aureus was the most common bacteria grown. The presence of crusting and hypervascularity was not dependent on the type of bacterial growth and there was no relation between hypervascularity and crusting of the nasal mucosa. Thirty-six patients were evaluated for the outcome analysis. Resolution of bleeding was not dependent on nasal colonization; in patients with colonization, there was no difference between topical antibacterial and non-antibacterial treatments.
Conclusion:
Despite the high colonization rates, topical antibacterial treatment was not found superior to non-antibacterial treatment. Our study does not support the belief that bacterial colonization results in hypervascularity of the septal mucosa causing epistaxis since no relation was found between nasal colonization, hypervascularity and crusting. The role of bacterial colonization in pediatric epistaxis need to be further investigated and treatment protocols must be determined accordingly.
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