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Updated: Mar 18, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
Published on: January 11, 2020
18F-NaF PET/CT Images of Cardiac Metastasis From Osteosarcoma
Yi-Hsien Chou1, Kuan-Yin Ko, Mei-Fang Cheng
1From the Departments of *Nuclear Medicine, and †Oncology, National Taiwan University Hospital, Taipei, Taiwan; and ‡Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China.
Abstract:
Osteosarcomas are aggressive with a high incidence of recurrence and metastasis. Cardiac osteosarcoma metastasis is rare. We described a 17-year-old boy who had right distal femoral osteosarcoma with lung metastases. During follow-up, right ventricular (RV) metastasis was noted and confirmed by histopathological examination of the surgical specimen. F-NaF PET/CT was then arranged 1 month after debulking surgery for residual tumor survey. The images showed intense F-NaF uptake at RV region, suggestive of residual cardiac metastases.
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