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Detection and Identification of Single Molecules in Immunology and Immunohematology: Single (solution)-phase
U Demel1, Z Földes-Papp1, G P Tilz1
1a Clinical Immunology and Jean Dausset Laboratory , Graz University M.S. and Hospital , Auenbruggerplatz 8, A-8036 Graz , LKH , Austria.
Abstract:
In the Goodpasture experiment, we determined a probability of 99.1% of identifying one single immune complex. Under these conditions, a single molecule event is proven. There exist no instrumental assumptions of our approach on which the experiments themselves, the theoretical background or the conclusion are based on. Our results open up a broad field for analytics and diagnostics in solution, particularly in immunology and immunohematology.

