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Related Concept Videos

Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Cross-reactivity00:42

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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Active versus Passive Immunity01:31

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Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
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Microorganisms in Medicine and Therapeutics01:29

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Homogeneous Glycoconjugate Produced by Combined Unnatural Amino Acid Incorporation and Click-Chemistry for Vaccine Purposes
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Combination Vaccines.

S K Jatana1, Mng Nair2

  • 1Senior Advisor (Paediatrics), 151 Base Hospital, C/o 99 APO.

Medical Journal, Armed Forces India
|July 14, 2016
PubMed
Summary
This summary is machine-generated.

Vaccination prevents childhood infections, but multiple shots are costly. Combination vaccines and ideal oral vaccines offer solutions for affordable and accessible pediatric immunization.

Keywords:
Combination vaccinesImmunizationInfections

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Area of Science:

  • Pediatrics
  • Immunology
  • Vaccine Development

Background:

  • Infectious diseases remain a primary cause of death in children under five.
  • Vaccination is a key preventive measure, but current schedules involve numerous injections.
  • The high number of vaccines increases healthcare costs and pediatrician visit frequency.

Purpose of the Study:

  • To address the challenges of extensive vaccination schedules in children.
  • To explore combination vaccines as a practical solution.
  • To outline the characteristics of an ideal future vaccine for pediatric use.

Main Methods:

  • Review of current vaccination challenges and strategies.
  • Analysis of the potential of combination vaccines.
  • Definition of criteria for an ideal pediatric vaccine.

Main Results:

  • Combination vaccines can reduce the number of injections and associated costs.
  • An ideal vaccine would be oral, administered at birth, heat-stable, and affordable.
  • Developmental research focuses on creating such an ideal vaccine.

Conclusions:

  • Combination vaccines offer an immediate improvement over current multi-dose schedules.
  • The ultimate goal is a single, ideal oral vaccine for comprehensive childhood immunization.
  • Future vaccine research aims for improved accessibility, stability, and reduced side effects.