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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Prostate Cancer - What's New?

D Doddamani1, A Kayastha2

  • 1Classified Specialist (Surgery and Urosurgery), Army Hospital (R&R), New Delhi.

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|July 14, 2016
PubMed
Summary
This summary is machine-generated.

Prostate cancer screening using prostate specific antigen (PSA) aids early detection, improving outcomes. Advanced imaging and treatments like radical prostatectomy reduce mortality, while lifestyle changes and medications may lower incidence.

Keywords:
Prostate cancerProstate specific antigenRadical prostatectomyWatchful waiting

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Area of Science:

  • Uro-oncology
  • Cancer diagnostics
  • Preventive medicine

Background:

  • Prostate specific antigen (PSA) is a key tumor marker for prostate cancer diagnosis and prognosis.
  • Prostate cancer is prevalent, particularly in North America and Europe.
  • Early detection and treatment significantly improve patient quality of life and prevent deaths from metastatic disease.

Purpose of the Study:

  • To review the current landscape of prostate cancer diagnosis, treatment, and prevention strategies.
  • To highlight the role of PSA in early detection and prognosis.
  • To discuss advancements in imaging and therapeutic interventions.

Main Methods:

  • Review of screening studies and established treatment protocols for prostate cancer.
  • Analysis of diagnostic advancements including MRI and PET scans.
  • Examination of preventive measures such as 5-alpha reductase inhibitors and lifestyle modifications.

Main Results:

  • Radical prostatectomy and laparoscopic radical prostatectomy are standard treatments for localized prostate cancer, reducing mortality.
  • Advanced imaging techniques like MRI and PET enhance the detection of cancer spread.
  • Lifestyle changes and medications like finasteride are being explored to reduce prostate cancer incidence.

Conclusions:

  • Early detection of prostate cancer through PSA screening and advanced imaging is crucial.
  • Effective treatments like radical prostatectomy improve survival rates.
  • Preventive strategies, including medication and lifestyle changes, are important for reducing prostate cancer incidence and promoting men's health.