Related Experiment Video
Updated: Mar 18, 2026

The Use of Thermal Infra-Red Imaging to Detect Delayed Onset Muscle Soreness
Published on: January 22, 2012
Is Lactic Acid Related to Delayed-Onset Muscle Soreness?
Abstract:
In brief: The authors tested the hypothesis that delayed-onset muscular soreness after running is related to the production of lactic acid during the exercise. Blood lactic acid concentration was measured before and during 45 minutes of treadmill running, one time on the level and once at a-10% incline. Blood lactic acid concentration and subjective sensations of muscular soreness were assessed at intervals for 72 hours after the runs. Lactic acid concentration was significantly increased during running on the level, but subjects experienced no significant postexercise muscular soreness. Lactic acid was never elevated in downhill runners, but subjects experienced significant delayed-onset soreness. Results indicated that lactic acid is not related to exercise-induced delayed-onset muscle soreness.
Related Concept Videos
Muscle Recovery and Fatigue
Local Anesthetics: Mechanism of Action
Local anesthetics are amphiphilic molecules consisting of a hydrophobic aromatic part linked to a hydrophilic group by an ester or amide linkage. They are weak bases and are usually available as salts, which increases their solubility and stability. Once administered, LAs exist in the body either...
Relaxation of Skeletal Muscles
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
Long-term Potentiation
Long-term Potentiation
Hebbian LTP
LTP can occur when...
Local Anesthetics: Differential Sensitivity of Nerve Fibers

