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Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance
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Metal-Organic Framework Coatings as Cytoprotective Exoskeletons for Living Cells
Kang Liang1, Joseph J Richardson2, Jiwei Cui3
1CSIRO Manufacturing, CSIRO Private Bag 10, Clayton South, Victoria, 3169, Australia. kang.liang@csiro.au.
Advanced Materials (Deerfield Beach, Fla.)
|July 15, 2016
Abstract:
The biomimetic mineralization of metal-organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal.
