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Updated: Mar 17, 2026

08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
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Novel melanoma therapies and their side effects
Noelani González1, Désirée Ratner2
1Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Cutis
|July 15, 2016
Abstract:
In the last few years, melanoma treatment has been revolutionized by the development of immune checkpoint-blocking antibodies or immune checkpoint inhibitors including ipilimumab, vemurafenib, dabrafenib, trametinib, nivolumab, and pembrolizumab. Although they have shown promising results, they also have caused multiple adverse events (AEs), particularly immune-related AEs (irAEs). Specialists should be familiar with these AEs.
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