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Surveillance following Focal Therapy interventions.

A W Postema1, M Catellani2, M J V Scheltema1

  • 1Department of Urology. AMC University Hospital. Amsterdam. The Netherlands.

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|July 15, 2016
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Summary
This summary is machine-generated.

Focal therapy (FT) for prostate cancer requires a minimum 5-year follow-up. Careful monitoring of oncologic and functional outcomes is crucial to ensure safety and efficacy of this tissue-sparing treatment.

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Area of Science:

  • Oncology
  • Urology
  • Medical Technology

Background:

  • Focal therapy (FT) offers a tissue-sparing approach for localized prostate cancer (PCa).
  • FT aims to improve functional outcomes while maintaining oncologic safety.
  • Standardized follow-up protocols are essential for evaluating FT's long-term effectiveness.

Purpose of the Study:

  • To provide an overview of key considerations for post-focal therapy follow-up.
  • To offer practical recommendations for monitoring patients treated with FT for prostate cancer.

Main Methods:

  • Literature review of studies on focal therapy for prostate cancer.
  • Analysis of data from Medline/PubMed database.

Main Results:

  • A minimum 5-year follow-up is recommended after FT.
  • Oncologic assessment includes PSA monitoring, multiparametric MRI, and biopsies; significant PCa detected in up to 17% of patients.
  • Functional outcomes (urinary, erectile, quality of life) are assessed via questionnaires, with reported continence in 83-100% and erections in 54-100%.

Conclusions:

  • Stringent follow-up is necessary to confirm the oncologic safety of focal therapy.
  • Standardized data collection and pooling are vital to assess FT's potential for improved functional outcomes and oncologic safety.