Related Experiment Video
Updated: Oct 29, 2025

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
Published on: June 30, 2023
Close proximity risk assessment for SARS-CoV-2 infection
G Cortellessa1, L Stabile1, F Arpino1
1Department of Civil and Mechanical Engineering, University of Cassino and Southern Lazio, Cassino, FR, Italy.
Maintaining safe interpersonal distance is crucial for reducing respiratory virus transmission. This study reveals that longer exposure times necessitate greater distances, with social distances of 1 meter becoming risky for exposures exceeding one minute.
Area of Science:
- Fluid dynamics
- Infectious disease transmission
- Risk assessment
Background:
- Interpersonal distance is key in respiratory virus spread.
- Mechanisms of droplet exposure are not fully understood.
- SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) risk assessment needs further characterization.
Purpose of the Study:
- To present an integrated risk assessment for SARS-CoV-2 exposure.
- To model the spread of exhaled droplets from a speaking person.
- To validate the model with experimental data.
Main Methods:
- Developed a 3D transient numerical model for droplet spread.
- Incorporated a SARS-CoV-2 emission model.
- Validated the numerical model using Particle Image Velocimetry (PIV) measurements.
Main Results:
- Large droplet risk is negligible beyond 0.6 m.
- Risk at greater distances depends solely on airborne droplets.
- Recommended safety distances increase with exposure duration: 0.75 m (10s), 1.1 m (1 min), 1.5 m (15 min).
Conclusions:
- Close proximity exposure risk is dependent on distance and duration.
- Social distances (approx. 1 m) pose a risk for exposures over 1 minute.
- Cultural and environmental factors influence interpersonal distances and risk.
Related Concept Videos
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Relative Risk
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

