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Assessing the global threat from Zika virus
Justin Lessler1, Lelia H Chaisson2, Lauren M Kucirka3
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. justin@jhu.edu.
Science (New York, N.Y.)
|July 16, 2016
Summary
Zika virus (ZIKV) infection, once obscure, gained global attention due to its link to microcephaly. This review examines ZIKV
Area of Science:
- Epidemiology
- Virology
- Public Health
Background:
- Zika virus (ZIKV) was first identified in 1947 but remained a lesser-known tropical disease.
- A significant increase in microcephaly cases in Brazil in 2015 brought global attention to ZIKV.
- Limited understanding exists regarding factors influencing the global threat of ZIKV infection and its complications.
Purpose of the Study:
- To review current knowledge on the epidemiology and natural history of ZIKV infection.
- To assess the public health impact of ZIKV.
- To identify critical knowledge gaps concerning ZIKV.
Main Methods:
- Literature review of existing studies on Zika virus.
- Analysis of epidemiological data related to ZIKV outbreaks.
- Synthesis of information on the natural history and clinical manifestations of ZIKV infection.
Main Results:
- The review consolidates information on ZIKV's epidemiology and natural history.
- Public health effects and the empirical basis of current knowledge are discussed.
- Key areas requiring further research are highlighted.
Conclusions:
- A comprehensive understanding of ZIKV's epidemiology and natural history is crucial.
- Addressing knowledge gaps is essential for mitigating the global threat of ZIKV.
- Further research is needed to fully comprehend and manage ZIKV infection and its consequences.
