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Uveitis in Chinese Patients with Psoriasis
Peizeng Yang1, Minming Zheng1, Lijun Zhang1
1a The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, and Chongqing Eye Institute , Chongqing , P.R. China.
Ocular Immunology and Inflammation
|July 16, 2016
Summary
Uveitis frequently affects patients with psoriasis in China, particularly those with psoriasis vulgaris and psoriatic arthritis. Psoriasis onset typically precedes uveitis, with anterior uveitis being the most common presentation.
Area of Science:
- Ophthalmology
- Dermatology
- Clinical Medicine
Background:
- Psoriasis is a chronic inflammatory disease with potential systemic manifestations.
- Ocular involvement, such as uveitis, can occur in patients with psoriasis.
- Understanding the clinical characteristics of uveitis in psoriatic patients is crucial for diagnosis and management.
Purpose of the Study:
- To investigate the clinical features of 51 patients with psoriasis and uveitis in China.
- To analyze the association between different types of psoriasis and uveitis presentation.
Main Methods:
- Retrospective analysis of 51 uveitis patients with psoriasis.
- Classification based on psoriasis type: psoriasis vulgaris, psoriatic arthritis, psoriatic erythroderma, and pustular psoriasis.
- Evaluation of demographics, ocular findings, auxiliary examinations, complications, and treatment outcomes.
Main Results:
- The study included 37 males and 14 females.
- Psoriasis vulgaris (29 cases) and psoriatic arthritis (15 cases) were the most common psoriasis types associated with uveitis.
- Psoriasis onset age was significantly younger than uveitis onset age (p < 0.001).
- Anterior uveitis was the most frequent type (58.8%), followed by panuveitis (35.3%) and posterior uveitis (5.9%).
- Hypopyon was more common in psoriatic arthritis patients (p = 0.007), and optic disc staining in psoriatic erythroderma (p = 0.029).
- Significant visual improvement was noted in 17 patients.
Conclusions:
- Uveitis is a significant ocular complication associated with various forms of psoriasis in China.
- Psoriasis vulgaris and psoriatic arthritis are the most frequently observed psoriasis types linked to uveitis.
- Early recognition and management of uveitis in psoriatic patients are essential for visual preservation.
