Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent development in non-ionic contrast media.

B Hagen

    Annales De Radiologie
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Iotrolan, a hypoosmolal contrast agent, caused less pain than hyperosmolar iopromide and ioxaglate during angiography. However, iotrolan

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    How it feels to be a dairy farmer: A cross-sectional survey of farm management and well-being of dairy farmers in Western Canada and Ontario.

    Journal of dairy science·2026
    Same author

    Not your average dairy farmer: Clustering dairy farmers of Western Canada and Ontario based on management practices and well-being.

    Journal of dairy science·2026
    Same author

    Setup of a Contamination Control Strategy Using the Hazard Analysis Critical Control Point (HACCP) Methodology.

    PDA journal of pharmaceutical science and technology·2023
    Same author

    Fertility and gonadal function after adjuvant therapy in women diagnosed with a malignant ovarian germ cell tumor (MOGCT) during the "cisplatin era".

    Gynecologic oncology·2014
    Same author

    [Disease management programs in Germany: validity of the medical documentation].

    Deutsche medizinische Wochenschrift (1946)·2014
    Same author

    Analysis of morphometrical features of macroconidia fromFusarium spp.

    Mycotoxin research·2013
    Same journal

    [Radiodiagnosis and irradiated pregnancies].

    Annales de radiologie·1997
    Same journal

    [Secret information provided by lumbosacral myelography].

    Annales de radiologie·1997
    Same journal

    [Diagnosis of calcified deposits in soft tissues].

    Annales de radiologie·1997
    Same journal

    [Myositis ossificans circumscripta and its variants].

    Annales de radiologie·1997
    Same journal

    [SAPHO syndrome and aseptic osteitis].

    Annales de radiologie·1997
    Same journal

    [The hand and rheumatism].

    Annales de radiologie·1997
    See all related articles

    Area of Science:

    • Radiology and Imaging
    • Pharmacology
    • Medical Devices

    Background:

    • Contrast media are essential for diagnostic imaging.
    • Osmolality and viscosity are key properties influencing contrast agent performance and patient experience.
    • Iotrolan, iopromide, and ioxaglate are commonly used iodinated contrast agents with varying properties.

    Purpose of the Study:

    • To compare the properties of iotrolan (hypoosmolal) with iopromide and ioxaglate (hyperosmolar) in selective peripheral angiography.
    • To evaluate patient-reported pain and opacification quality.
    • To assess the incidence of systemic reactions.

    Main Methods:

    • Selective peripheral angiography was performed.
    • Properties of iotrolan, iopromide, and ioxaglate were comparatively studied.

    Related Experiment Videos

  • Patient-reported pain and opacification were assessed.
  • Systemic and anaphylactoid reactions were monitored.

    • Main Results:

    • Iopromide and ioxaglate (twice blood osmolality) induced significantly more pain than iotrolan (isotonic).
    • Mild painful reactions with iotrolan may be psychological.
    • High viscosity of iotrolan delayed peripheral opacification.
    • No systemic or anaphylactoid reactions were observed for any agent.

    Conclusions:

    • Iotrolan offers a potentially better safety profile regarding pain compared to iopromide and ioxaglate.
    • The high cost and viscosity of iotrolan are important considerations for its clinical selection.
    • Further research may explore strategies to mitigate iotrolan's viscosity for improved opacification.