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Published on: February 14, 2022
Long-term non-invasive ventilation in children
Alessandro Amaddeo1, Annick Frapin2, Brigitte Fauroux1
1Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker Enfants-Malades, Paris, France; Paris Descartes Faculty, Paris, France; Research Unit INSERM U955, Créteil, France.
Insights
Long-term non-invasive ventilation (NIV) is increasingly used in children for respiratory issues. Management requires specialized multidisciplinary centers due to diverse patient needs and conditions.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Biomedical Engineering
Background:
- Long-term non-invasive ventilation (NIV) use in pediatric populations is rising globally.
- NIV delivers ventilatory support via a non-invasive interface for various respiratory conditions.
- Indications span central drive dysfunction, respiratory muscle weakness, and increased respiratory load disorders.
Purpose of the Study:
- To review the expanding use and indications of long-term non-invasive ventilation in children.
- To discuss the selection criteria for NIV based on pathophysiological features and technical aspects.
- To emphasize the necessity of specialized multidisciplinary care for pediatric NIV patients.
Main Methods:
- Literature review on the current trends and applications of pediatric non-invasive ventilation.
- Analysis of indications, including central drive issues, muscle weakness, and increased respiratory load.
- Discussion of technical considerations (interface, device) and management strategies.
Main Results:
- Non-invasive ventilation (NIV) is indicated for diverse pediatric respiratory failures, requiring tailored approaches.
- The choice of NIV modality depends on the specific pathophysiology, such as replacing central drive or supporting respiratory muscles.
- Effective NIV management necessitates careful selection of interfaces and devices.
Conclusions:
- The heterogeneity of pediatric respiratory conditions necessitates individualized NIV strategies.
- Management of children requiring long-term NIV demands expertise in specialized multidisciplinary centers.
- Expertise in sleep studies and patient therapeutic education is crucial for optimal outcomes in pediatric NIV.
Abstract:
Use of long-term non-invasive ventilation is increasing exponentially worldwide in children of all ages. The treatment entails delivery of ventilatory assistance through a non-invasive interface. Indications for use of non-invasive ventilation include conditions that affect normal respiratory balance (eg, those associated with dysfunction of the central drive or respiratory muscles) and disorders characterised by an increase in respiratory load (eg, obstructive airway or lung diseases). The type of non-invasive ventilation used depends on the pathophysiological features of the respiratory failure. For example, non-invasive ventilation will need to either replace central drive if the disorder is characterised by an abnormal central drive or substitute for the respiratory muscles if the condition is associated with respiratory muscle weakness. Non-invasive ventilation might also need to unload the respiratory muscles in case of an increase in respiratory load, as seen in upper airway obstruction and some lung diseases. Technical aspects are also important when choosing non-invasive ventilation-eg, appropriate interface and device. The great heterogeneity of disorders, age ranges of affected children, prognoses, and outcomes of patients needing long-term non-invasive ventilation underline the need for management by skilled multidisciplinary centres with technical competence in paediatric non-invasive ventilation and expertise in sleep studies and therapeutic education.
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