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Biphasic flow-volume loop in granulomatosis with polyangiitis related unilateral bronchus obstruction
Abhinav Agrawal1, Sonu Sahni2, Galina Marder3
1Monmouth Medical Center, Department of Medicine, 300 s Avenue Long Branch, NJ 07740, USA.
Abstract:
Spirometry flow-volume measurement is used routinely in the outpatient setting to rule out obstructive lung diseases. Biphasic flow-volume loop is a classic presentation of unilateral bronchial stenosis due to multiple etiologies and it should raise clinical suspicion. Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition with pulmonary manifestations that may be infiltrative (e.g., pneumonia), hemorrhagic, and may rarely cause bronchial stenosis. Herein, we present a case of GPA-related, bronchial obstruction that caused biphasic flow-volume loop along with a literature review.
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