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Genetic testing in veterinary dermatology.

Tosso Leeb1,2, Eliane J Müller2,3,4, Petra Roosje2,5

  • 1Vetsuisse Faculty, Institute of Genetics, University of Bern, Bremgartenstrasse 109a, Bern, 3001, Switzerland.

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Genetic testing is revolutionizing veterinary diagnostics for hereditary skin diseases in pets. Understanding genetic test applications is crucial for accurate diagnosis and responsible breeding practices.

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Area of Science:

  • Veterinary Genetics
  • Dermatology
  • Animal Genomics

Background:

  • Significant advancements in molecular genetics have enhanced the study of hereditary skin diseases.
  • Veterinary genetics offers new tools for diagnosing and managing animal dermatoses.

Purpose of the Study:

  • To update veterinarians on genetic tests for skin diseases in dogs, cats, and horses.
  • To guide the selection and application of genetic tests in clinical practice.

Main Methods:

  • Critical review of scientific literature.
  • Compilation of causative variants for genodermatoses using the Online Mendelian Inheritance in Animals (OMIA) database.

Main Results:

  • Genetic testing is a vital diagnostic tool in veterinary medicine.
  • Genetic tests aid in diagnosing diseases with non-specific signs and support sustainable breeding programs.
  • Genome-wide screening is advancing for research and anticipated in clinical practice.

Conclusions:

  • Understanding the application and interpretation of genetic tests is essential for clinicians.
  • As DNA and genome-wide analyses become more common, proper interpretation is critical for veterinary care.