Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Somatosensation01:33

Somatosensation

44.8K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
44.8K
Cerebral Hemispheres01:05

Cerebral Hemispheres

2.9K
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
2.9K
Lateralization01:28

Lateralization

1.2K
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
1.2K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

3.3K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiovascular Responses to Natural and Auditory Evoked Slow Waves Predict Post-Sleep Cardiac Function.

Journal of sleep research·2026
Same author

Transcutaneous Auricular Vagus Nerve Stimulation during Movement Selectively Activates Motor Circuitry without Additional Cortical or Autonomic Effects.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Autism subtypes identified using cross-species functional connectivity analyses.

Nature neuroscience·2026
Same author

The relationship between exposure to long-term training, neuromuscular function and muscular structure in adolescents with cerebral palsy and typically-developed peers: a cross-sectional follow-up analysis.

BMC musculoskeletal disorders·2026
Same author

Finger tapping at maximal speed evokes crossover fatigability in the other hand.

Frontiers in human neuroscience·2026
Same author

Pupil-based arousal self-regulation: impact on physiological and affective responses to emotional stimuli.

Translational psychiatry·2026
Same journal

Identification of polyamine metabolism-related gene signatures for prognostic and immunological stratification in glioma.

Neuroscience·2026
Same journal

Age- and sex-dependent effects of single prolonged stress on behavioral, hematological, and oxidative stress parameters in C57BL/6J mice.

Neuroscience·2026
Same journal

Accelerated long-term forgetting and relevant biomarkers for early detection in preclinical Alzheimer's disease.

Neuroscience·2026
Same journal

Deciphering key factors contributing to age-related decline in visuomotor tracking through the manipulation of target refresh rate and gaze contingency.

Neuroscience·2026
Same journal

LPI alleviates Alzheimer's disease pathology via the GPR55 receptor.

Neuroscience·2026
Same journal

Blood-brain barrier dysfunction in surgery and anesthesia: a potential mechanistic contributor to postoperative cognitive dysfunction.

Neuroscience·2026
See all related articles

Related Experiment Video

Updated: Mar 17, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

12.7K

Interhemispheric sensorimotor integration; an upper limb phenomenon?

Kathy L Ruddy1, Ellen Jaspers1, Martin Keller2

  • 1Neural Control of Movement Lab, ETH Zurich, Switzerland.

Neuroscience
|July 19, 2016
PubMed
Summary
This summary is machine-generated.

Short latency afferent inhibition (SAI) occurs in the upper limb via transcallosal pathways. This sensorimotor integration process was absent in the lower limb, suggesting limb-specific differences.

Keywords:
inhibitionipsilateralsensorimotor integrationshort latency afferent inhibitionsomatosensory

More Related Videos

Author Spotlight: Enhancing Neurorehabilitation Through EEG, Motor Imagery, and Virtual Reality
10:14

Author Spotlight: Enhancing Neurorehabilitation Through EEG, Motor Imagery, and Virtual Reality

Published on: May 10, 2024

2.0K
Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
09:42

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

2.3K

Related Experiment Videos

Last Updated: Mar 17, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

12.7K
Author Spotlight: Enhancing Neurorehabilitation Through EEG, Motor Imagery, and Virtual Reality
10:14

Author Spotlight: Enhancing Neurorehabilitation Through EEG, Motor Imagery, and Virtual Reality

Published on: May 10, 2024

2.0K
Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
09:42

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

2.3K

Area of Science:

  • Neuroscience
  • Motor Control
  • Somatosensory System

Background:

  • Somatosensory information travels to the primary sensory cortex (S1) with specific delays.
  • Transcranial Magnetic Stimulation (TMS)-induced motor evoked potentials (MEPs) show inhibition upon sensory input arrival.
  • Short latency afferent inhibition (SAI) is a phenomenon reflecting sensorimotor interactions.

Purpose of the Study:

  • To investigate sensorimotor integration in the hemisphere ipsilateral to the stimulated limb using SAI.
  • To determine if SAI in the ipsilateral hemisphere is mediated by transcallosal pathways.
  • To explore potential limb-specific differences in bilateral sensorimotor integration.

Main Methods:

  • Electrical stimulation of the limb (contralateral or ipsilateral to TMS) at various interstimulus intervals (ISIs).
  • Measurement of SAI effects on motor evoked potentials (MEPs) in the First Dorsal Interosseous (FDI) muscle (hand) and Tibialis Anterior (TA) muscle (lower leg).
  • Analysis of SAI onset timing in relation to contralateral SAI and transcallosal conduction delays.

Main Results:

  • Ipsilateral SAI was observed in the upper limb (FDI) at ISIs greater than N20+18ms.
  • No ipsilateral SAI was detected in the lower limb (TA) across tested ISIs.
  • The timing of ipsilateral SAI in the upper limb suggests mediation by transcallosal communication.

Conclusions:

  • Transcallosal pathways likely mediate ipsilateral SAI in the upper limb.
  • The absence of ipsilateral SAI in the lower limb indicates potential limb-specific differences in sensorimotor integration.
  • Further research is needed to understand the functional implications of these limb-specific differences.