Related Experiment Video
Updated: Mar 17, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
Published on: May 9, 2025
Problems Faced by Antiretroviral (ARV) Drug Users in Kathmandu
1Nepalese Army Institute of Health Science, College of Nursing, Kathmandu, Nepal.
Background:
Antiretroviral Therapy (ART) offers an opportunity to improve the prognosis and quality of life of People Living with HIV/AIDS (PLHIV). However, inability to achieve adherence even after drug introduction in Nepal is a matter of concern. Some efforts are to be applied in order to lend a hand to identify and minimize these problems. This study aims to assess the problems faced by antiretroviral drug users attending ART centers of Kathmandu.
Methods:
A descriptive study was carried out in Sukraraj Tropical and Infectious Disease Control Hospital, Teku and Bir Hospital in 2071. Non-probability convenience sampling technique was used to recruit 82 respondents. Semi-structured questionnaire was used for conducting the interview.
Results:
The overall problems faced by antiretroviral drug users include side-effects of drugs (65.9%), long waiting time (24.4%), unsatisfactory service (4.9%), geographical (68.3%) and financial barrier (25.6%), etc. Few were turned off from social/religious (70.7%) and recreational activities (51.2%). Absence of disclosure (14.6%), lack of spousal support (10.9%), humiliation (34.1%), etc. were also present. Stigmatization materializes as having to lose job (8.5%), feeling of ashamed (30.5%), feeling of isolation (34.1%), etc. Adherence towards medicine was found to be 86.5%.
Conclusions:
ART is a long term process and to achieve it rationally, a user has to cope with lots of problems, associated not only with physical health but also with outcomes of psychosocial issue. Further worsening of the situation is due to financial constraints. Policy making, planning and service delivery seek improvement in various steps. Awareness is another demand to end psychosocial discrimination.
Related Concept Videos
Retrovirus Life Cycles
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics: Drug–Drug Interactions
Therapeutic Drug Monitoring: Affecting Factors
Pharmacokinetics: Drug–Food and Drug–Viral Interactions

