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Updated: Mar 17, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Is Sudden Hearing Loss Associated with Atherosclerosis?
Mohsen Rajati1, Mahmoud Reza Azarpajooh2, Mohsen Mouhebati3
1Sinus and Surgical Endoscopic Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sudden sensorineural hearing loss (SSNHL) may be linked to subclinical atherosclerosis. Increased intima media thickness and HSCRP levels were observed in SSNHL patients, suggesting a potential vascular component.
Area of Science:
- Otolaryngology
- Cardiovascular Medicine
- Vascular Biology
Background:
- Sudden sensorineural hearing loss (SSNHL) affects 2-3% of ENT referrals.
- Vascular disorders and compromised perfusion are potential predisposing factors for SSNHL.
- This study investigates atherosclerotic changes and risk factors in SSNHL patients.
Purpose of the Study:
- To explore the association between subclinical atherosclerosis and SSNHL.
- To identify cardiovascular risk factors in patients with SSNHL.
- To compare atherosclerotic markers between SSNHL patients and controls.
Main Methods:
- A case-control study involving 30 SSNHL patients and 30 controls.
- Assessment of cardiovascular risks: medical history, physical examination, blood pressure, BMI, waist circumference, ECG, blood sugar, lipids, and HSCRP.
- Carotid artery color Doppler ultrasound to measure intima-media thickness (IMT).
Main Results:
- SSNHL patients exhibited significantly higher IMT and HSCRP levels compared to controls (P=0.005 and P=0.001, respectively).
- No significant differences were found in smoking history, waist circumference, fasting blood sugar, lipid profile, or ECG between groups.
- Interestingly, controls had higher blood pressure and BMI than SSNHL patients.
Conclusions:
- Subclinical atherosclerosis may be associated with sudden sensorineural hearing loss.
- Elevated IMT and HSCRP suggest a role for vascular changes in SSNHL.
- Further research is warranted to elucidate the relationship between atherosclerosis and hearing loss.
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