Sarcoid arthropathy in cystic fibrosis

An 8-year-old boy with cystic fibrosis presented with a chronic polyarthritis. Histological examination of the synovium demonstrated multiple non-caseating granulomata. A systematic search for sarcoidosis revealed characteristic ophthalmic abnormalities and an elevated serum level of angiotensin converting enzyme. An association between cystic fibrosis and sarcoidosis is likely.