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Updated: Mar 17, 2026

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
Published on: July 28, 2023
Use of several immunological markers to model the probability of active tuberculosis
Elisa Petruccioli1, Assunta Navarra2, Linda Petrone1
1Translational Research Unit, Department of Epidemiology, Preclinical Research and Advanced Diagnostics, "L. Spallanzani" National Institute for Infectious Diseases (INMI) IRCCS, Via Portuense 292, Rome, 00149, Italy.
Abstract:
Blood-based biomarkers tests are attractive alternative for diagnosing tuberculosis to assays depending on mycobacteria detection. Given several immunological markers we used logistic regression to model the probability of active tuberculosis in a cohort of patients with active or latent tuberculosis, showing an increased accuracy in distinguishing active from latent tuberculosis.
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