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Prevalence of Atopic Dermatitis in Chinese Children aged 1-7 ys
Yifeng Guo1, Ping Li2, Jianping Tang3
1Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Insights
The prevalence of childhood atopic dermatitis (AD) in China is 12.94% based on clinical diagnosis. This nationwide study highlights a significant increase in AD cases among Chinese children.
Area of Science:
- Pediatric Dermatology
- Epidemiology
- Public Health
Background:
- Global prevalence of atopic dermatitis (AD) is rising.
- Previous studies on AD in China lacked face-to-face, nationwide data.
- Understanding the prevalence in Chinese children is crucial for public health initiatives.
Purpose of the Study:
- To determine the prevalence of clinically diagnosed atopic dermatitis in children aged 1-7 years across China.
- To compare clinical diagnosis prevalence with established diagnostic criteria.
- To provide the first nationwide, face-to-face epidemiological data on childhood AD in China.
Main Methods:
- A nationwide study involving 13,998 children aged 1-7 years from 12 major Chinese metropolises.
- Random selection of kindergartens and vaccination clinics for data collection.
- Diagnosis and severity assessment by dermatologists using UK diagnostic criteria, characteristic, and atypical presentations.
Main Results:
- The overall prevalence of clinically diagnosed atopic dermatitis was 12.94%.
- Mild AD accounted for 74.6% of cases.
- Prevalence based on UK diagnostic criteria was 4.76%, differing from clinical diagnosis.
Conclusions:
- The prevalence of childhood atopic dermatitis in China is substantial, approaching levels seen in wealthier nations.
- This study provides critical, first-time nationwide data on childhood AD in China.
- Clinical diagnosis yields a higher prevalence than strict adherence to UK criteria, suggesting variations in diagnostic practices.
Abstract:
Prevalence of atopic dermatitis (AD) is increasing worldwide. Up to date, there has been no face-to-face nation-wide study in China. We aim to explore the prevalence of clinical diagnosed AD in children aged 1-7 ys in China. Twelve metropolises were chosen from different areas of China. In each region, we selected 4-10 kindergartens and 2-5 vaccination clinics randomly. A complete history-taking and skin examination were performed by dermatologists. The definite diagnosis of AD and the severity were determined by two or three dermatologists. All criteria concerned in UK diagnosis criteria, characteristic presentation of AD and atypical manifestations were recorded in detail. A total of 13998 children from 84 kindergartens and 40 vaccination clinics were included. The prevalence of AD was 12.94% by clinical diagnosis of dermatologists overall, with 74.6% of mild AD. Comparatively, prevalence of AD based on UK diagnostic criteria was 4.76%. This is the first face-to-face nation-wide study in Chinese children aged 1-7 ys, revealing that the prevalence of AD in children is closer to that of wealthier nations.
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