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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Positron Emission Tomography.

Katherine Lameka1, Michael D Farwell2, Masanori Ichise3

  • 1Department of Radiology, Tufts University, Boston and Department of Radiology, Baystate Medical Center, Springfield, MA, USA.

Handbook of Clinical Neurology
|July 20, 2016
PubMed
Summary
This summary is machine-generated.

Positron emission tomography (PET) offers advanced 3D imaging of biological function, unlike CT or MRI which focus on anatomy. This review details PET principles and its neurological applications.

Keywords:
(18)F-FDGPET/CTPET/MRIcoincidence detectionneuroimagingpositron emission tomography

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Area of Science:

  • Nuclear medicine
  • Medical imaging
  • Radiochemistry

Background:

  • Positron emission tomography (PET) is a functional imaging technique.
  • PET visualizes radiopharmaceutical distribution, offering insights into metabolic and molecular processes.
  • It contrasts with anatomical imaging modalities like MRI and CT.

Purpose of the Study:

  • To provide an overview of PET physics, instrumentation, and its integration with anatomical imaging (CT/MRI).
  • To focus on the clinical applications of PET in neurologic disorders.
  • To discuss PET scan interpretation and findings in various neurological conditions.

Main Methods:

  • Review of basic physics principles and instrumentation of PET.
  • Discussion of radiopharmaceuticals, including (18)F-fluorodeoxyglucose for glucose metabolism.
  • Focus on clinical neurologic disorders and relevant PET findings.

Main Results:

  • PET enables 3D mapping of radiopharmaceuticals for functional imaging.
  • Integration with CT/MRI enhances diagnostic accuracy by combining functional and anatomical data.
  • PET findings are detailed for dementias, epilepsy, movement disorders, infections, cerebrovascular disorders, and brain tumors.

Conclusions:

  • PET is a valuable tool for studying biological function in health and disease.
  • Its application in neurology aids in the diagnosis and understanding of various disorders.
  • The combination of PET with CT/MRI provides comprehensive diagnostic information.