Related Experiment Video
Updated: Mar 17, 2026

09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
5.0K
Acute Renal Failure Following a Marathon.
The Physician and Sportsmedicine
|July 20, 2016
Summary
Even with extensive training, a runner experienced acute kidney injury after their first marathon. This case highlights the potential risks of endurance events on renal health.
Area of Science:
- Nephrology
- Sports Medicine
- Exercise Physiology
Background:
- Marathon running is a demanding endurance activity.
- Athletes undergo rigorous training regimens.
- Acute kidney injury (AKI) can occur in athletes.
Purpose of the Study:
- To report a case of acute kidney injury in a marathon runner.
- To discuss potential risk factors and mechanisms.
Main Methods:
- Case report presentation.
- Review of relevant medical literature.
Main Results:
- The runner developed AKI post-marathon despite thorough preparation.
- Potential contributing factors such as dehydration and rhabdomyolysis were considered.
Conclusions:
- Endurance events pose a risk for AKI, even in well-trained individuals.
- Close monitoring of renal function in athletes is important.
Related Concept Videos
Acute Kidney Injury I: Introduction
1.1K
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
1.1K
Dialysis
1.8K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
1.8K
Acute Kidney Injury III: Clinical Manifestations
1.2K
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
1.2K
Acute Kidney Injury II: Pathophysiology
1.6K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.6K
Acute Kidney Injury V: Interprofessional Care
450
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
450
Acute Kidney Injury IV: Diagnostic Studies and Prevention
452
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
452

