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Published on: December 18, 2012
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Recurrent Kikuchi's Disease Treated by Hydroxychloroquine.
Miri Hyun1, In Tae So1, Hyun Ah Kim1
1Department of Infectious Disease, Keimyung University School of Medicine, Daegu, Korea.
Infection & Chemotherapy
|July 20, 2016
Summary
Kikuchi-Fujimoto disease (KFD), a self-limiting condition, typically presents with fever and swollen lymph nodes. This case highlights successful hydroxychloroquine (HC) treatment for KFD unresponsive to steroids.
Area of Science:
- Immunology
- Pathology
- Rheumatology
Background:
- Kikuchi-Fujimoto disease (KFD) is a rare, benign, and self-limiting disorder.
- KFD is characterized by fever and cervical lymphadenopathy, with histopathological findings of necrotizing lymphadenitis.
- Standard treatment involves conservative management, with steroids or NSAIDs used for persistent symptoms.
Purpose of the Study:
- To report a case of Kikuchi-Fujimoto disease (KFD) in a patient unresponsive to conventional steroid therapy.
- To evaluate the efficacy of hydroxychloroquine (HC) as an alternative treatment for steroid-resistant KFD.
Main Methods:
- A clinical case study of a 25-year-old female patient diagnosed with KFD.
- Review of previous literature on KFD treatment, particularly hydroxychloroquine (HC) use.
- Documentation of treatment response to HC after failure of steroid therapy.
Main Results:
- The patient presented with symptoms consistent with KFD and did not respond to steroid treatment.
- Successful management of KFD symptoms was achieved using hydroxychloroquine (HC).
- This case supports the potential of HC in treating refractory KFD.
Conclusions:
- Kikuchi-Fujimoto disease (KFD) can be challenging to manage when unresponsive to steroids.
- Hydroxychloroquine (HC) offers a viable therapeutic option for steroid-resistant KFD.
- Further research may explore HC's role in KFD management.
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