Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Initial Design of a Self-Retracting Trocar for Distal Ventriculoperitoneal Catheter Insertion.

Cureus·2026

Same author

Low Utility and Yield of Routine Outpatient CT Imaging in Patients With Mild Traumatic Brain Injury and Intracranial Hemorrhage.

Cureus·2025

Same author

We Tabulated and Organized American Board of Neurological Surgeons Primary Exam Keywords (2015-2023) so You Don't Have to.

Cureus·2023

Same author

Chronic subdural hematoma drainage using anti-thrombotic catheter technique.

World neurosurgery: X·2023

Same author

Neurologic Outcomes for Octogenarians Undergoing Emergent Surgery for Traumatic Acute Subdural Hematoma.

World neurosurgery·2022

Same author

Elective Endovascular Treatment of Unruptured Intracranial Aneurysms.

Cureus·2022

Same journal

Retraction: The Association Between Janus Kinase 2 and Factor V Leiden Mutations and Thrombotic Complications in Patients With Myeloproliferative Disorders: A Study From Saudi Arabia.

Cureus·2026

Same journal

Patient-Reported Understanding of Emergency Department Discharge Instructions, Satisfaction, and Acceptability of a Future Telemedicine-Based Call-Back Program: Phase 1 Observational Pilot Study at a Tertiary Hospital in Dubai, United Arab Emirates.

Cureus·2026

Same journal

Correction: Methylprednisolone-Induced Delayed and Sustained Bradycardia in Multisystem Inflammatory Syndrome in Children.

Cureus·2026

Same journal

Rapid Interval Development of a Left Hepatic Artery Pseudoaneurysm During Acute Interstitial Edematous Pancreatitis.

Cureus·2026

Same journal

Recurrent Acute Pancreatitis Secondary to Untreated Hyperparathyroidism: A Case Report and Literature Review.

Cureus·2026

Same journal

A Prospective Case-Control Study of Helicobacter pylori and Systemic Inflammation in Colorectal Cancer Pathogenesis.

Cureus·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 17, 2026

Author Spotlight: Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Author Spotlight: Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Published on: May 26, 2023

Germinoma with Diffuse Subependymal Spread: A Case Report.

Evan M Krueger¹, Darbi L Invergo¹, Julian J Lin²

¹Neurosurgery, Advocate Health Care.

|July 20, 2016

Summary

This summary is machine-generated.

A rare pure germinoma presented with diffuse ventricular seeding, mimicking other pathologies. Prompt diagnosis and radiation therapy led to significant clinical improvement and tumor burden reduction.

Keywords:

diffuse subependymal intracranial germinoma pineal suprasellar ventricles

More Related Videos

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Published on: November 11, 2021

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Related Experiment Videos

Last Updated: Mar 17, 2026

Author Spotlight: Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Author Spotlight: Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Published on: May 26, 2023

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Published on: November 11, 2021

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Area of Science:

Neuro-oncology
Pediatric Neurology
Radiology

Background:

Germinomas are rare germ cell tumors, more prevalent in Asian populations.
They typically present as midline masses, with diffuse ventricular seeding being uncommon.

Observation:

A 19-year-old male presented with headaches and syncope, showing pineal/suprasellar masses and diffuse subependymal enhancement on imaging.
Cerebrospinal fluid analysis was non-specific, necessitating further investigation.

Findings:

Neuroendoscopic biopsy confirmed a pure germinoma.
The patient showed significant clinical improvement and tumor regression after radiation therapy.

Implications:

This case highlights the importance of considering germinoma in cases of diffuse subependymal lesions, even with negative tumor markers in CSF.
Histopathologic diagnosis via endoscopic biopsy is crucial for definitive diagnosis in the US.
Germinomas demonstrate high sensitivity to radiation and chemotherapy, offering a favorable prognosis.