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PHOTODYNAMIC THERAPY FOR CHOROIDAL NEVUS WITH SUBFOVEAL FLUID
Renelle Pointdujour-Lim1, Arman Mashayekhi, Jerry A Shields
1Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
Retina (Philadelphia, Pa.)
|July 20, 2016
Summary
Photodynamic therapy (PDT) effectively manages subfoveal fluid in choroidal nevus, with 87% of patients showing fluid resolution. This treatment offers a safe option for improving vision in these cases.
Area of Science:
- Ophthalmology
- Medical Retina
- Ocular Oncology
Background:
- Choroidal nevus is a common benign intraocular tumor.
- Subfoveal fluid associated with choroidal nevus can impair visual acuity.
- Effective management strategies for this condition are crucial.
Purpose of the Study:
- To evaluate the efficacy of photodynamic therapy (PDT) for managing subfoveal fluid in patients with choroidal nevus.
- To assess visual acuity outcomes and fluid resolution rates following PDT.
Main Methods:
- Retrospective chart review of 15 patients with choroidal nevus and subfoveal fluid.
- Treatment with standard-fluence photodynamic therapy (PDT).
- Assessment of treatment response using optical coherence tomography (OCT).
Main Results:
- Complete resolution of subfoveal fluid occurred in 60% of eyes, with partial resolution in 27%.
- Visual acuity improved in 53% of patients post-PDT.
- 33% of patients required a second PDT session.
Conclusions:
- Photodynamic therapy (PDT) is a safe and effective treatment for subfoveal fluid associated with choroidal nevus.
- PDT achieves high rates of fluid resolution, contributing to visual improvement.
- Further research is warranted to define the optimal role and limitations of PDT in this context.
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