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Best Practices for Intrathecal Baclofen Therapy: Screening Test.

Aaron L Boster¹, Susan E Bennett², Gerald S Bilsky³

¹OhioHealth Neurological Physicians, Columbus, OH, USA.

Neuromodulation : Journal of the International Neuromodulation Society

|July 20, 2016

Summary

Intrathecal baclofen (ITB) screening evaluates patient response to a test dose for spasticity and function. This process helps identify suitable candidates for ITB therapy and potential adverse reactions.

Keywords:

Clinical protocols consensus implantable infusion pump intrathecal baclofen muscle spasticity spinal

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Area of Science:

Neurology
Pharmacology
Rehabilitation Medicine

Background:

Intrathecal baclofen (ITB) therapy is a treatment for spasticity.
Screening is essential to assess patient response and identify potential adverse reactions before ITB pump implantation.

Purpose of the Study:

To outline best practices for intrathecal baclofen screening.
To guide the identification of appropriate candidates for ITB therapy.

Main Methods:

An expert panel reviewed existing literature and conducted an online survey.
Established best practices for ITB screening procedures and candidate selection.

Main Results:

Successful ITB screening may confirm or modify patient goals related to mobility, function, and pain.
Testing requires careful consideration of patient medical status and baclofen dosage, with frequent monitoring for adverse events like hypotension and respiratory depression.
Pre-implantation discussions must cover all aspects of ITB therapy, including device specifics and patient commitment.

Conclusions:

ITB screening is a critical step in identifying suitable candidates for intrathecal baclofen therapy.
Effective screening ensures optimal outcomes and patient safety.