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[ANALYSIS OF MICROFLORA OF PLEURAL CAVITY IN PLEURAL EMPYEMA]

I V Chubar

    Klinichna Khirurhiia
    |July 21, 2016
    PubMed

    Insights

    Pleural empyema (PE) treatment faces challenges in identifying pathogens and restoring lung function. Increased resistance to common antibiotics necessitates the use of more potent, costly drugs for effective PE management.

    Area of Science:

    • Infectious Diseases
    • Pulmonology
    • Microbiology

    Context:

    • Pleural empyema (PE) treatment remains complex despite advances in surgical and medical interventions.
    • Key challenges include accurate pathogen identification, rapid bronchial fistula closure, and lung volume restoration.

    Purpose:

    • To analyze the spectrum of infectious agents in pleural empyema.
    • To assess the sensitivity of these agents to various antimicrobial preparations.
    • To identify trends in antibiotic resistance, including methicillin-resistant Staphylococcus aureus (MRSA).

    Summary:

    • The study identified the spectrum of infectious agents responsible for PE and their susceptibility patterns.
    • A significant increase in methicillin-resistant Staphylococcus aureus (MRSA) and microbial associations was observed.
    • Reduced sensitivity of causative agents to standard antibiotics was confirmed, indicating a need for advanced antimicrobial agents.

    Impact:

    • Findings highlight the challenges in treating PE due to evolving microbial resistance.
    • The reduced efficacy of common antibiotics necessitates the use of broader-spectrum, more expensive 'hard' antibiotics.
    • This shift impacts treatment costs and underscores the need for updated therapeutic guidelines for PE.

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