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Native and engineered promoters in natural product discovery

Maksym Myronovskyi1, Andriy Luzhetskyy

  • 1Helmholtz-Institute for Pharmaceutical Research Saarland, Saarland University Campus, Building E8 1, 66123 Saarbrücken, Germany. a.luzhetskyy@mx.uni-saarland.de.

Natural Product Reports
|July 21, 2016
PubMed
Summary

Activating silent gene clusters in Streptomyces bacteria is key to discovering new natural products. This study reviews promoters that enable the expression of these silent clusters for therapeutic development.

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