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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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DBS for Obesity.

Ruth Franco1, Erich T Fonoff2, Pedro Alvarenga3

  • 1Division of Pediatric Endocrinology, Children's Hospital, University of São Paulo Medical School, São Paulo 05403-000, Brazil. franco.ruth@icloud.com.

Brain Sciences
|July 21, 2016
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) shows promise for treating severe obesity when other methods fail. This review explores DBS targets, outcomes, and future potential for refractory obesity.

Keywords:
deep brain stimulationhypothalamusnucleus accumbensobesity

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Area of Science:

  • Neuroscience
  • Surgical Innovation
  • Metabolic Disorders

Background:

  • Obesity is a complex, chronic disease with significant health risks.
  • Pharmacological and behavioral treatments for morbid obesity often yield limited success.
  • Bariatric surgery, while effective, carries risks and potential side effects.

Purpose of the Study:

  • To review the potential of deep brain stimulation (DBS) for medically refractory obesity.
  • To examine the rationale behind selecting specific brain targets for DBS in obesity.
  • To discuss surgical outcomes and future directions for DBS in obesity treatment.

Main Methods:

  • Review of existing literature on deep brain stimulation (DBS) for neuropsychiatric disorders.
  • Analysis of studies investigating DBS for obesity treatment.
  • Evaluation of different brain targets and their efficacy.

Main Results:

  • Deep brain stimulation (DBS) is an emerging neurosurgical option for severe obesity.
  • Specific brain targets are being investigated for their effectiveness in modulating appetite and metabolism.
  • Early results suggest potential, but further research is needed.

Conclusions:

  • Deep brain stimulation (DBS) offers a novel therapeutic avenue for patients with severe, treatment-resistant obesity.
  • Continued research into optimal brain targets and surgical techniques is crucial.
  • DBS may represent a future treatment modality for managing this complex metabolic disorder.