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Updated: Mar 17, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Special Situations in Pulmonary Hypertension: Pregnancy and Right Ventricular Failure
Jana Svetlichnaya1, Munir Janmohammed1, Teresa De Marco1
1Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Abstract:
Despite rapid advances in medical therapy, pregnancy and right ventricular (RV) failure predicts a poor prognosis in patients with pulmonary arterial hypertension. Evidence-based therapy for pulmonary arterial hypertension should be initiated early in the disease course to decrease RV wall stress and prevent RV remodeling and fibrosis. In patients with acutely decompensated RV failure, an aggressive and multifaceted approach must be used; a thorough search for triggering factors for the decompensation is a key part of the successful management strategy. Patients with refractory RV failure who are not candidates for surgical intervention should be referred to palliative care to maximize quality of life and symptom relief.
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