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[Electrophoretic mobility of the cells of non-T, non-B acute lymphoblastic leukemia]
Abstract:
In order to ascertain the possibility of the use of electrophoretic mobility (EPM) as one of the criterion for delicate identification of the leukemic cell, a study was made of the EPM of blast cells having an approximately equal status of differentiation. A study was also made of lymphoblasts of the most frequently occurring variant of acute lymphoblastic leukemia, namely of the non-T, non-B variant. It has been established that the given cells are marked by the similar values of the EPM, which greatly exceed the analogous characteristics of normal mature B lymphocytes, being lower as compared with the EPM of T lymphocytes. The data obtained indicate that it is advisable to apply the EPM for identification of the leukemic clone in acute lymphoblastic leukemia.