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Giant rectal polyp prolapse in an adult patient with the Peutz-Jeghers syndrome

Ana Delfina Cano-Contreras1, Arturo Meixueiro-Daza2, Peter Grube-Pagola3

  • 1Labortorio de Fisiologia DIgestiva y Motilidad, Instituto de Investigaciones Medico Biologicas, Veracruz, Mexico.

BMJ Case Reports
|July 23, 2016
PubMed

Insights

Peutz-Jeghers Syndrome (PJS) can cause rare rectal complications in adults. A 30-year-old man with PJS presented with severe anal pain and bleeding due to a giant prolapsed polyp.

Area of Science:

  • Gastroenterology
  • Genetics
  • Clinical Medicine

Background:

  • Peutz-Jeghers Syndrome (PJS) is an autosomal dominant disorder.
  • It is characterized by hamartomatous polyps and mucocutaneous pigmentation.
  • Rectal prolapse of polyps is a rare complication, especially in adults.

Observation:

  • A 30-year-old male patient with a recent PJS diagnosis presented to the emergency department.
  • He reported sudden severe anal pain, a foreign body sensation, and rectal bleeding.
  • Physical examination confirmed a giant prolapsed polyp.

Findings:

  • The patient's symptoms were attributed to a giant prolapsed polyp.
  • This represents an extremely rare manifestation of Peutz-Jeghers Syndrome in an adult.

Implications:

  • Highlights the potential for rare, severe rectal complications in adult PJS patients.
  • Underscores the importance of considering PJS in the differential diagnosis of rectal prolapse with bleeding.
  • Suggests the need for vigilant monitoring and prompt management of rectal issues in PJS patients.

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