Related Experiment Video
Updated: Mar 17, 2026
In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
Multimodal imaging in a case of self-inflicted laser-induced maculopathy
France Combillet1,2, Valentine Saunier1, Marie Bénédicte Rougier1
1Department of Ophthalmology, CHU de Bordeaux, Bordeaux - France.
Purpose:
To describe the clinical and imaging findings in a case of self-inflicted handheld laser exposure.
Methods:
We evaluated multimodal imaging including fundus autofluorescence, spectral-domain optical coherence tomography (SD-OCT), fluorescein angiography, and indocyanine green angiography for a 32-year-old man with a history of repetitive self-inflicted handheld laser exposure.
Results:
Funduscopic examination revealed bilateral and asymmetric yellow macular linear streaks with a vertical pattern in the superior macula. Curvilinear bands of dense hyperreflectivity extending from the ellipsoid zone of the photoreceptors and ending at the level of the outer plexiform layer were seen on SD-OCT immediately after injury. After intravenous high-dose corticosteroids during 3 days, the lesions decreased slightly.
Conclusions:
The recognition of characteristic self-inflicted handheld laser-induced lesions is paramount as laser pointer misuse has been increasing over the years.
More Related Videos
12:22Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
10:14Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023