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Updated: Mar 17, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
To whom is HIV pre-exposure prophylaxis proposed?
Oskar Ayerdi-Aguirrebengoa1, Mar Vera-García2, Teresa Puerta-López2
1Servicio de Urgencias, Hospital Fundación Jiménez Díaz, Madrid, España; Unidad de ITS/VIH, Centro Sanitario Sandoval IdISSC, Madrid, España.
Introduction:
HIV Pre-Exposure Prophylaxis (PrEP) consists of administering antiretroviral drugs to seronegative individuals with high risk practices. The aim of the study was to describe the characteristics of recent seroconverted HIV patients in order to determine the profile of the appropriate candidates for PrEP.
Methods:
A descriptive study of all patients diagnosed with HIV infection in 2014, and who had achieved a documented negative serology over the previous 12 months. A specific form was completed to determine the sociodemographic, behavioural, and clinical features, with complementary tests being performed for other sexually transmitted infections.
Results:
Almost all (98.4%) of the 61 recent seroconverted were men who have sex with men, and aged between 20 to 39 years (88.5%). They also had a background of sexually transmitted infections (80.3%), performed multiple and unprotected sexual practices (82.7%), and under the effect of recreational drugs (87%).
Conclusions:
The evaluation of the risk factors for HIV infection in seronegative patients should enable the appropriate candidates for PrEP to be identified.
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