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A second case of neonatal alloimmune thrombocytopenia associated with anti-PlA2 (Zwb) antibodies
K Maslanka1, G F Lucas, A Gronkowska
1Institute of Haematology, Warsaw, Poland.
Haematologia
|January 1, 1989
Abstract:
A case of neonatal alloimmune thrombocytopenia due to fetomaternal incompatibility against the platelet specific antigen PlA2 (Zwb) is described. Anti-PlA2 antibodies were present in the maternal serum together with anti-HLA antibodies. Initial identification of the platelet-specific antibodies was achieved by using chloroquine-treated PlA1(+) and PlA1(-) platelets. Antibody specificity was later confirmed using a panel of platelets of known phenotype.