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Updated: Mar 17, 2026
Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
Automated motion correction using parallel-strip registration for wide-field en face OCT angiogram.
Pengxiao Zang1, Gangjun Liu2, Miao Zhang2
1Casey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA; Shandong Province Key Laboratory of Medical Physics and Image Processing Technology, Institute of Biomedical, Sciences, School of Physics and Electronics, Shandong Normal University, Jinan, 250014, China.
We developed a new method to fix motion artifacts in wide-field optical coherence tomography angiography (OCTA) scans. This technique improves image clarity for better analysis of retinal vasculature.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Wide-field optical coherence tomography angiography (OCTA) is crucial for visualizing retinal vasculature.
- Motion artifacts degrade image quality and hinder accurate analysis in OCTA.
- Ultrahigh-speed swept-source OCT (>200 kHz A-scan rate) enables rapid acquisition but is susceptible to motion artifacts.
Purpose of the Study:
- To introduce an innovative registration method for correcting motion artifacts in wide-field OCTA.
- To enhance image quality and enable precise analysis of retinal vasculature from OCTA data.
- To develop a robust technique for processing ultrahigh-speed OCTA scans.
Main Methods:
- A non-orthogonal registration scheme was developed, considering the high number of A-scans along the fast axis in wide-field OCTA.
- En face angiograms were divided into parallel strips, processed with gross and fine registration based on vessel structures.
- The method was extended for automatic montage of motion-free angiograms into an ultrawide-field view.
Main Results:
- The proposed registration method effectively corrects motion artifacts in wide-field OCTA.
- Sequential gross and fine registration accurately aligns parallel strips into a composite image.
- The technique enables the automatic creation of motion-free, ultrawide-field OCTA montages.
Conclusions:
- The developed registration method significantly improves the quality of wide-field OCTA images by correcting motion artifacts.
- This technique provides a reliable approach for analyzing retinal vasculature in ultrahigh-speed OCTA acquisitions.
- The automated montage capability facilitates the generation of comprehensive ultrawide-field retinal imaging.
