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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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Related Experiment Video

Updated: Mar 17, 2026

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
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Do Athletes Need Influenza Vaccines?

C C Johnson

    The Physician and Sportsmedicine
    |July 23, 2016
    PubMed
    Summary

    Influenza in athletes can lead to missed practice and games, impacting team performance. Physicians present information, allowing athletes to decide on managing their illness and return to play.

    Area of Science:

    • Sports Medicine
    • Infectious Disease

    Background:

    • Influenza (flu) significantly impacts athletes, causing missed training and competition.
    • The decision for athletes to play while ill involves balancing health risks and competitive needs.

    Purpose of the Study:

    • To explore the considerations for athletes managing influenza.
    • To understand the role of team physicians in guiding athlete decisions regarding influenza.

    Main Methods:

    • Review of current literature on influenza in athletes.
    • Analysis of clinical guidelines for return-to-play protocols.

    Main Results:

    • Influenza can lead to prolonged recovery and reduced athletic capacity.
    • Physicians often provide factual information rather than directives.

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    Conclusions:

    • Athletes face a critical decision-making process when ill with influenza.
    • Informed choices by athletes are crucial for managing influenza and maintaining team readiness.