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Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Ophthalmic manifestations of tuberous sclerosis: a review
Nickisa Hodgson1,2, Michael Kinori1, Michael H Goldbaum2
1Department of Ophthalmology, Ratner Children's Eye Center of the Shiley Eye Institute, University of California, San Diego, California, USA.
Abstract:
Tuberous sclerosis or tuberous sclerosis complex (TSC), one of the phakomatoses, is characterized by hamartomas of the heart, kidney, brain, skin and eyes. Ophthalmologic examinations are required in all cases of TSC. Retinal hamartomas are the most common ocular finding in tuberous sclerosis. The majority of hamartomas are non-progressive; however, lesions with subretinal fluid and progression have been reported. This paper details the genetics, clinical features and ocular findings of TSC and reviews potential therapeutic options for ophthalmic manifestations.
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