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Updated: Mar 17, 2026

Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry
09:38

Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry

Published on: June 26, 2019

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Stem-loop binding protein is a multifaceted cellular regulator of HIV-1 replication.

Ming Li, Lynne D Tucker, John M Asara

    The Journal of Clinical Investigation
    |July 26, 2016
    PubMed
    Summary

    Researchers found that lower levels of stem-loop binding protein (SLBP) in HIV-1 patients correlate with higher viral loads. Restoring SLBP may offer a new therapeutic strategy for HIV-1 infection by impacting histone metabolism and inflammation.

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