[Anti-osteoporotic drugs and their interactions with multiple organs]
1Endocrine Center, Toranomon Hospital, Tokyo, Japan.
None:
Anti-osteoporotic drugs directly control bone metabolism. Then, they are possibly involved in interactions between bone and many other tissues. It is not, however, clear how they influence several organs other than bone, or what clinical significance they have. Recently, accumulating evidence suggests that osteocalcin as a humoral factor from bone is actively involved in glucose metabolism. Since interaction between osteoporosis and diabetes mellitus is an emerging clinical issue, there are several clinical questions under vigorous investigations.
Related Concept Videos
Drug toxicity: Drug–Drug Interaction
Drug Distribution: Tissue Binding
For...
Pharmacokinetics: Drug–Drug Interactions
Factors Affecting Protein-Drug Binding: Drug Interactions
Displacement interactions can have varying outcomes, ranging from toxicity to virtually...
Combined Effects of Drugs: Antagonism
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism


